Abstract

Clinical Summary: A 49 year old man presents with a history of subacute vertigo and acute mild traumatic head injury. His medical history included rheumatoid arthritis, for which he was taking methotrexate, and a tonsillar lesion not yet diagnosed.
Imaging revealed multiple periventricular and intraventricular lesions, which were hyperdense on computer tomography imaging and avidly gadolinium-enhancing on magnetic resonance imaging. A right temporal craniectomy was performed, and tissue diagnosis was made. Treatment was initiated but proved unsuccessful, and the patient died two months after initial
presentation.

What is/are?

1 : Differential diagnosis?